An anti-impotence drug approved by the United States Food and Drug Administration and available by prescription in mid-April 1998 raised hopes for millions of men who suffer from a type of impotence known as erectile dysfunction, the inability to obtain and maintain an erection. Analysts expected Sildenafil Citrate, produced by Pfizer, Inc. under the name Viagra, to become one of the best-selling drugs in history.
The drug provides an alternative to previous impotence treatments, such as penile implants and injections, which many patients found uncomfortable or inconvenient. For that reason, and because of its high success rate and relatively minor side effects such as headaches and upset stomach, many physicians characterized the new drug as a major breakthrough in the treatment of erectile dysfunction.
In recent times, the proliferation of internet sites offering the drug for sale at bargain prices have brought about a sea change in the availability of the drug to end-users. Buying cheap Viagra online is fast and a convenient way of remaining anonymous. It saves you the embarrassment of paying a visit to the doctor or pharmacist and the drug would be delivered to your office or home in a non-descript package. However, before taking the decision, it’s sensible to take the following steps.
Step One: Conduct a research
Before you Purchase Viagra tablets online, ensure that it’s safe for you to take the blue pill. For instance, there are existing medical conditions such as stroke that make the administration of the drug dangerous. Also, like other medications, Sildenafil citrate is contraindicated for other drugs. You could learn about its dangerous drug interactions and also obtain detailed information on the drug by visiting Pfizer’s official Viagra site. Alternatively, if you are on any medications, it makes a lot of sense to consult with your family doctor or pharmacist before making the purchase.
Step Two: Patronise an online Pharmacy with a good reputation
The obvious thing for you to do is to choose an online pharmaceutical company with a good reputation. The advantage of getting a reputable online pharmacy, with licensed physicians and pharmacists, is that you’d be getting the best value for your money in the area of offering honest, reliable service. An online pharmacy that readily comes to mind is emedsRX.com.
Step Three: Answer the Health Questionnaire
When you are Buying Viagra online without prescription, the online pharmacy can help provide one for you. They usually do this by making you answer a medical questionnaire, which is usually detailed to ensure your safety when you are taking the pill. It is noteworthy to mention that the information you provide should be full and accurate, because your safety depends on it. They usually charge you a fee for this service, but that would only be if your prescription is approved. If your prescription is rejected, then you will not be charged.
Step Four: Carefully select your dosage
Viagra is manufactured in three dosages of 25 mg, 50 mg, and 100 mg. The most cost-effective practice of buying Viagra is to buy the 100 mg pills and cutting them into halves or fourths. For this purpose, you can purchase cutters at your local store or simply use a knife. In some cases, the drug comes with a pill splitter. Always remember that 100 mg is a high dose; it’s advisable to start with a quarter pill (25 mg) before increasing the dose.
Step Five: Place Your Order
After you've answered the medical questionnaire, a doctor would review your order before deciding on your prescription. Once your prescription is approved, place your order. Your Viagra will be delivered to you in a couple of days. Overall, the entire process of online purchase is relatively straightforward, and the benefits of safe usage of the wonder pill are usually worth the steps taken.
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At the mention of erectile dysfunction, one could be forgiven if the only thing that comes to one’s mind is Viagra. Such is the popularity of this brand that close substitutes struggle to come out of the shadow of a drug that has imprinted its name in the minds of a greater proportion of a sexually conscious populace. Considering that the discovery of the drug could at best be described as serendipitous, this is by no means an ordinary feat by any stretch of the imagination.
Synthesised by a group of pharmaceutical chemists working at Pfizer’s Sandwich, Kent, research facility in the UK, Sildenafil was initially studied for use in hypertension and angina pectoris (a symptom of ischaemic heart disease). After the first clinical trials were conducted in Morrison Hospital, Swansea, it was discovered that Sildenafil was ineffective for angina. However, participants in the study noted a surprising side effect: the drug induced penile erection among men who were impotent. This discovery prompted the decision by Pfizer to market the drug for erectile dysfunction rather than for angina.
After taking out a patent on it in 1996, under the brand name Viagra, Sildenafil was approved for use in erectile dysfunction by the US FOOD and Drug Administration on March 27, 1998: hence ushering in a sea change in the oral treatment of ED, not only in the US but the world over. Buy Viagra cheap UK
Ever since it was introduced into the US market, Best Viagra tablets have brought about significant impact for a great percentage of the male populace who will at some point in their lives face the complete inability to achieve or maintain an erection. This condition, which becomes more prevalent with age, has the effect of making sexual intercourse difficult, if not impossible. Although proved medical interventions have been available for more than 20 years, recent advances in the understanding of the processes that lead to an erection have spurred new treatments and promise even more targeted therapies in the future.
Even though Sildenafil is available only by prescription from a doctor, it was advertised directly to consumers on U.S. TV (famously being endorsed by former United States Senator Bob Dole and soccer Pele). Numerous sites on the Internet offer Viagra for sale after an "online consultation", often a simple web questionnaire. Buy Viagra online no prescription.
The "Viagra" name has become so well known that many fake aphrodisiacs now call themselves "herbal Viagra" or are presented as blue tablets imitating the shape and colour of Pfizer's product. Viagra is also informally known as "Vitamin V", "the Blue Pill", as well as various other nicknames.
In recent times, Pfizer explored various new ways of administering the drug, such as nasal and wafer delivery systems that may allow for more rapid absorption, thus reducing the waiting time for an erection. Meanwhile other researchers are testing different oral medications. A drug called apomorphine, which stimulates the hypothalamus to induce erection, is being tested in the form of a tablet that dissolves in the mouth—an attempt to minimize its main side effects of nausea and vomiting. Phentolamine, currently used as a stand-alone and combination injectable drug, is also being tested in an oral form.
Pfizer's worldwide patents on sildenafil citrate will expire in 2011–2013. The UK patent held by Pfizer on the use of PDE5 inhibitors as treatment of impotence was invalidated in 2000 because of obviousness; this decision was upheld on appeal in 2002.
In February 2007, it was announced that Boots the Chemist would trial over the counter sales of Viagra in stores in Manchester, England. Men aged between 30 and 65 would be eligible to buy four tablets after a consultation with a pharmacist.
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Introduction
Since real Viagra tablets were approved in the US and became available as a prescription drug in the middle of April, 1998, and its subsequent success, there has been a renewed interest in the treatment of erectile dysfunction (ED), especially through the oral route of administration. A prominent drug in the market is Tadalafil – trade name: Cialis. A quick look at the ED drug market shows that a new drug, Vardenafil – trade name: Levitra – has jumped on the bandwagon. Judging by the potency of Viagra – Buy Viagra online next day delivery – and Levitra in treating patients with ED problem, both have become household names with the same mechanism of action in inhibiting phoshodiesterase and boosting the effects of nitric oxide, a chemical compound that is known to relax the penile musculature. There are however individual features that distinguish these drugs from one another.
Different Owners
While Levitra is manufactured by Bayer Corp., it is distributed by GlaxoSmith Kline. Viagra is invented and marketed by the drug manufacturing giant Pfizer.
Approval by FDA
The Food and Drug Administration has approved both Levitra and Viagra as prescription drugs for the treatment of erectile dysfunction. However, while Viagra was approved by the regulatory authority in March 1998, Levitra was approved in August 2003, a much later date.
Potency in treating Erectile Dysfunction
As said earlier, both Levitra and Viagra have almost the same mechanism of action, with both chemically formulated to inhibit the enzyme phosphodiesterase type 5 (PDE5), as well as enabling the penis to become rock hard, which is necessary for sexual penetration and intercourse. They can both be used by patients suffering from hypertension and diabetes and those who are to undergo prostrate surgery. However where the two drugs differ are in the times it takes both to act and how long they can stay in the system after administration. While Viagra is normally taken one hour before sexual intercourse and can stay in the system for four hours, Levitra can be taken about thirty minutes before intercourse and is slightly longer-acting, staying up to five hours in the system.
Dosage difference
Both Levitra and Viagra are prescription drugs, to be administered under the instructions of medical practitioners. Levitra comes in doses of 2.5mg, 5mg, and 20mg. Viagra tablets are available in comparatively larger doses of 25mg, 50mg, and 100mg.
Active ingredients
The active ingredient in Viagra – Buy Viagra cheap prices – is Sildenafil citrate, while that of Levitra is Vardenafil.
The cost it takes to procure the pills
The two drugs have similar prices.
Rate of success
The two drugs have as high as 70 percent success rate. However, phosphodiesterase inhibitors do not work for everybody. Some men may need to seek alternative treatments like vacuum pump devices or penile implants in some cases.
What are their side effects?
The two drugs have similar side effects. Cases of facial flushing, headaches, back pain, stomach aches, runny stomach, and even changes in vision – studies have shown that there have been rare incidences of patients seeing some tinges of blue, but which went away after the drugs had been eliminated from the system – have been reported. These side effects, though common, should not be enough reasons for worry.
However, these two drugs shouldn’t be taken in combination with low blood pressure drugs since they have the synergistic abilities to potentiate heart attack. In addition, a high blood pressure patient who wants to take any of these two PDE-5 inhibitors should do so only after consulting a physician.
How do these two drugs look like?
Viagra is a small blue pill with the engraving of its manufacturer’s name – Pfizer – in the middle. Levitra is an orange tablet and has a flame logo.
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